ABSTRACT
Wegener's granulomatosis (WG) classically consists of necrotizing granulomatous inflammation of the upper and/or lower respiratory tract, necrotizing glomerulonephritis, and an autoimmune necrotizing systemic vasculitis affecting predominantly small vessels. We report a case of WG with central nervous system (CNS) involvement. WG is being diagnosed through pulmonary nodule biopsy. A small nodular lesion in the left posterior basal ganglia of brain being highly suspicious for granulomatosis was detected by MRI. After IV pulse cyclophosphamide and oral corticosteroid treatment for over 4 months, clinical manifestations and CNS lesions in brain MRI is improved. WG might have multiple granulomatous lesions which could be misdiagnosed due to malignancy. CNS involvement in WG is rare but careful evaluation is necessary when there are suspicious symptoms or lesions in CNS.
Subject(s)
Basal Ganglia , Biopsy , Brain , Central Nervous System , Cyclophosphamide , Glomerulonephritis , Inflammation , Lung , Lung Neoplasms , Neoplasm Metastasis , Respiratory System , Systemic Vasculitis , Granulomatosis with PolyangiitisABSTRACT
PURPOSE: The purpose of the study was to investigate fatigue, depression and sleep in young adult and middle-aged. METHOD: The convenient sample consisted of 415 subjects from 20 to 59 years old. Data were collected using a self-report questionnaire from July to October, 2001. The VAS-F and CES-D were utilized to measure the level of fatigue and depression. Sleep duration and sleep satisfaction were measured based on the subject's self-report. RESULT: The result of the study revealed that the level of fatigue and depression was higher among young adult than middle-aged. Considering age and gender, the level of fatigue and depression was higher among young adult women and middle-aged men. Depression and sleep satisfaction influenced on the fatigue. CONCLUSION: Health care providers need to concern about fatigue and depression in young adult women and middle-aged men. Especially, more concern and intervention programs are needed for young adult women and middle-aged men.
ABSTRACT
PURPOSE: This descriptive study was designed to investigate Body Mass Index(BMI), weight control behavior, and self-esteem in high school adolescents. METHOD: The convenience sample consisted of 129 high school females and 106 high school males. Data were collected using a self-report questionnaire from November to December, 1999. BMI was calculated by using the subject's self-reported body weight and height to identify objective obesity. Self evaluation about subjective obesity was measured by a single item question. Preferred BMI was calculated by using the subject's self-reported body weight and height which the subjects desired. The Rosenberg's Self-Esteem Scale was utilized to measure the level of self-esteem. RESULTS: Results of the study revealed that high school females perceived themselves as more more obese than their the actual BMI, excessively participated in dieting behavior and exercises, and reported lower self-esteem than that of males. CONCLUSION: Based on this study, health care providers need to educate female adolescents about healthy behavior as well as the normal weight range in BMI.
Subject(s)
Adolescent , Female , Humans , Male , Body Mass Index , Body Weight , Diagnostic Self Evaluation , Diet , Exercise , Health Personnel , Obesity , Weight Loss , Surveys and QuestionnairesABSTRACT
PURPOSE: The purpose of the study was to investigate the effects of anxiety, depression and self-esteem on the amount of smoking and nicotine dependency among woman smokers. METHOD: The convenience sample consisted of 121 unmarried woman smokers. The STAI, the CES-D Scale, the Self-Esteem scale and the FTQ were utilized to measure the level of anxiety, depression, self-esteem, and nicotine dependency. The amount of smoking was calculated based on the number of cigarette used. RESULTS: Results indicated that woman smokers were depressed. Nicotine dependency was relatively low. Subjects had smoked a mean of 9.58 cigarettes per day. The level of depression influenced on smoking and nicotine dependency. Self-esteem influenced on the amount of smoking and anxiety influenced on nicotine dependency. CONCLUSION: The results of this study revealed that the amount of smoking of unmarried woman smokers was very high. Both the amount of smoking and nicotine dependency were affected by levels of depression. Education programs and campaigns are needed to prevent smoking of young adult women.
Subject(s)
Female , Humans , Young Adult , Anxiety , Depression , Education , Nicotine , Single Person , Smoke , Smoking , Tobacco ProductsABSTRACT
The clinico-pathological observation was done on 28 children with recurrent hematuria, who had been admitted to the Pediatric ward of NMC from January 1981 to July 1991. The results were as follows; 1) Most of the children with recurrent hematuria were over 6 years of age(24 cases, 85.7%)and the sex ratio was about 2.5:1. 2) IgA nephropathy (17 cases, 60.7%) was the leading pathologic lesion and mild focal nonspecific glomerulonephritis (5 cases), membranous nephropathy (2 cases), minimal chage (2 cases), Alport syndrome (1case), abnormal glomerular basement membrane (1 case) followed. 3) Types of recurrent hematuria ware gross in 22 cases and microscopic in 6 cases. Flank pain was noted only 1 case. The prodromal events of hematuria were upper respiratory infection in 15 cases and severe exercise in 2 cases. 4) There were no significant differences in clinical features and laboratory findings between IgA nephropathy and other pathologic lesions, except for higher frequency of proteinuria in former group. 5) During the follow-up periods, three cases were resulted in chronic renal failure and they were two cases of IgA nephropathy Class IV and one case of Alport syndrome. And one case of IgA nephropathy was resulted in nephrotic syndrom.
Subject(s)
Child , Humans , Flank Pain , Follow-Up Studies , Glomerular Basement Membrane , Glomerulonephritis , Glomerulonephritis, IGA , Glomerulonephritis, Membranous , Hematuria , Kidney Failure, Chronic , Nephritis, Hereditary , Proteinuria , Sex RatioABSTRACT
The symmetrical peripheral gangrene syndrome consists of sudden onset of symmetrical gangrene of the fingers, toes and more raely, the nose, upper lip, ear lobes, or genitalia. There is no evidence of occulusion of large vessels or vasculitis. We experienced a case of symmetrical peripheral gangrene developed in fingers and toes with disseminated intravascular coagulation in 20 day-old permature infant with sepsis by Enterobacter aerogenes. Thereafter, we presented a case with a brief review of the related literatures.